Suicide Prevention by Lithium - the Lithium Intervention Study

• Status: Terminated
• Trial end date: 2006-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the proposed suicide preventive effects of lithium in a randomized controlled trial within a group of individuals with depressive disorders. The hypothesis being tested is that lithium treatment will significantly reduce the risk for another suicide attempt.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Schleswig-Holstein; University of Schleswig-Holstein
• Collaborators: Charite University, Berlin, Germany; German Federal Ministry of Education and Research; Sanofi; Technische Universität Dresden; University of Bonn; University of Erlangen-Nürnberg
• Treatments: Lithium Carbonate

Criteria

Inclusion Criteria:

• suicide attempt within 3 months prior to the first drug administration

• occurrence of suicide attempt within the context of an affective spectrum disorder

• minimum age of 18 years

• ability to complete screening and baseline assessment

• ability to understand and provide informed consent

Exclusion Criteria:

• diagnosis of schizophrenia, borderline personality disorder, substance related disorders

• indication for long-term lithium treatment

• thyroid disease

• pregnancy and lactation