Sulforaphane-rich Broccoli Sprout Extract for Autism
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
The primary objectives of this study are to answer whether there is evidence of measurable
effects on social responsiveness (primary outcome) and other behavioral symptoms after
treatment of autistic male adolescents and adults with orally administered sulforaphane-rich
Broccoli Sprout Extract (efficacy). The secondary objectives of this study are to answer
whether treatment of male adolescents and adults with autism using orally administered
sulforaphane-rich Broccoli Sprout Extract within a specified dose range is safe (toxicity);
treatment with sulforaphane-rich Broccoli Sprout Extract is well tolerated (side effects and
adverse events); key cellular biomarkers support the hypothesized mechanisms (proof of
principle).
Phase:
Phase 2
Details
Lead Sponsor:
Andrew Zimmerman University of Massachusetts, Worcester