Superb Microvascular Imaging in Focal Nodular Hyperplasia
Status:
Completed
Trial end date:
2019-04-25
Target enrollment:
Participant gender:
Summary
Focal nodular hyperplasia (FNH) in liver is the second common benign hepatic tumor. It
usually shows hypervascular mass on imaging studies and it is not easy to differentiate with
other hypervascular malignant tumor. For diagnosis of FNH, contrast-enhanced ultrasonography
(US) has been used to detect 'spoke-wheel sign', which can be typically seen in FNH. However,
temporal window of vascular phase using contrast-enhanced US (CEUS) is very short (about 10
sec) and coordination of patient's respiration during US exam is absolutely needed. Thus, the
investigators will use Superb-Microvascular imaging (SMI, Toshiba, Japan) for detection of
'spoke-wheel sign' in patients with proven FNH, which enable to detect slow micro vascular
flow without using CEUS.
First, to compare the detection rate of 'spoke-wheel sign' between CEUS using sonazoid
(Perfluorobutane, GE healthcare) and SMI.
Second, to compare the accuracy of size measurement between gray-scale US and SMI (reference
standard: CEUS using sonazoid.)