Supervised Treadmill Exercise and Ranolazine for Intermittent Claudication of Lower Extremities
Status:
Terminated
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
The goal of this study is to evaluate whether supervised treadmill exercise combined with
ranolazine 1000 mg twice daily provides an incremental benefit in absolute walking distance
over supervised exercise alone in patients with stable claudication. Investigators also seek
to determine if the administration of ranolazine provides a sustained benefit after the
completion of a supervised exercise regimen. Lastly, investigators wish to determine whether
both exercise and ranolazine improves peak oxygen consumption and anaerobic threshold in
patients with stable claudication.