A study of how supplemental oxygen helps patients with acute pulmonary embolism (PE).
Hypothesis: Oxygen affects right ventricular dysfunction (RVD) in patients with acute
pulmonary embolism (PE) primarily by relieving hypoxic pulmonary vasoconstriction and
reducing pulmonary pressure (PA) pressure, and that this process is metabolically driven.
Phase:
Early Phase 1
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
National Heart, Lung, and Blood Institute (NHLBI) University of Aarhus