Supplemental Thyroxine Treatment for Preterm Infants With Hypothyroxinemia

• Status: Completed
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: All

Summary

In order to determine the efficacy and safety of thyroxine replacement, a randomized clinical trial of thyroxine supplementation for VLBW infant with hypothyroxinemia during the first month of age is conducted.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tokyo Women's Medical University
• Collaborator: Tokyo Metropolitan Bokuto Hospital

Criteria

Inclusion Criteria:

• Birth weight: less than 1500g

• Gestation: 22 weeks 0 day ≤

• Serum free thyroxine level lower than 0.8 ng/dl

• Serum thyrotropin lower than 10 μU/ml

• Age of between 2 and 4 weeks after birth

• Informed consent

Exclusion Criteria:

• any known thyroid disease in mother