Supplementation of Oil Palm Phenolics to Healthy Participants

• Status: Recruiting
• Trial end date: 2020-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Our previous study has found that oil palm phenolics (OPP) supplementation at 9 grams per day is safe for consumption. An interesting observation was reported where the consumption of OPP showed significantly lower total and LDL cholesterol compared to the control group. There is no clinical evidence as yet on the optimum dosage of OPP supplementation in improving fasting lipid profile. We hypothesize that in a clinical study, OPP supplemented participants will elicit a reduction in total and LDL cholesterol while maintaining safety and tolerability.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National University of Malaysia
• Collaborator: Malaysia Palm Oil Board

Criteria

Inclusion Criteria:

• Healthy

• Normal Total Cholesterol level of less than 5.2 mmol/dL

• Normal LDL Cholesterol level of less than 3.36 mmol/dL

• Normal Triglyceride level of less than 1.69 mmol/dL

Exclusion Criteria:

• Smoking

• Habitual alcohol consumption

• Consuming antioxidant supplement

• Pregnant/ breastfeeding

• Medical history of cardiovascular disease, diabetes, dyslipidemia

• Current use of antihypertensive or lipid-lowering medication