Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet

• Status: Not yet recruiting
• Trial end date: 2023-12-15
• Target enrollment: 0
• Participant gender: All

Summary

This study is conducted to test the hypothesis that patients with lung cancer undergoing immunotherapy receiving a high protein diet and supplemented with fish oil will improve muscle mass, therapeutic response and modulate the intestinal microbiota within a 4 month period.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Universidade Federal do Rio de Janeiro
• Collaborators: Grupo Oncoclínicas; Institutos Madrileño de Estudios Avanzados IMDEA; Oncoclínicas

Criteria

Inclusion Criteria:

• Diagnosis of non-small cell lung cancer, both sexes, ECOG performance status (0-1), treatment virgin, eligible for immunotherapy.

Exclusion Criteria:

• supplementation of PUFA n-3 in the last 6 months; weight loss> 10% in 6 months, chronic liver disease, previous chronic kidney disease, anorexia, decompensated diabetes mellitus and dementia.