Surfactant Positive Airway Pressure and Pulse Oximetry Trial
Status:
Completed
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
This study compared the use of continuous positive airway pressure initiated at birth with
the early administration of surfactant administered through a tube in the windpipe within 1
hour of birth for premature infants born at 24 to 27 weeks gestation. In addition, these
infants within 2 hours of birth, had a special pulse oximeter placed to continuously monitor
their oxygen saturation in two different target ranges (85-89% or 91-95%). This study helped
determine whether or not these two management strategies affect chronic lung disease and
survival of premature infants.
Phase:
Phase 3
Details
Lead Sponsor:
NICHD Neonatal Research Network
Collaborators:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) National Center for Research Resources (NCRR) National Heart, Lung, and Blood Institute (NHLBI)