Surgery With Our Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma
Status:
Recruiting
Trial end date:
2028-04-21
Target enrollment:
Participant gender:
Summary
This is a multicenter, randomized, open label phase lll trial to assess whether preoperative
chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk
DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease
free survival.
After confirmation of eligibility criteria, patients will be randomized to either the
standard arm or experimental arm.
Phase:
Phase 3
Details
Lead Sponsor:
European Organisation for Research and Treatment of Cancer - EORTC
Collaborators:
Anticancer Fund, Belgium Australia and New Zealand Sarcoma Association Canadian Cancer Trials Group Eastern Cooperative Oncology Group