Surgical Excision and Intralesional Steroid Injection for Prevention of Post Caesarean Keloid Recurrence

• Status: Completed
• Trial end date: 2018-01-24
• Target enrollment: 0
• Participant gender: Female

Summary

Two groups of patients (73 patients each) undergoing routine caesarean section has recurrent keloid at site of surgical scar. One group will undergo surgical excision of keloid. The other group will have combined surgical excision of keloid and single intralesional dexamethasone injection at edges of wound.All patients were reviewed once per month for 6 months for evidence of recurrence

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kasr El Aini Hospital
• Treatments: BB 1101; Dexamethasone; Dexamethasone acetate

Criteria

Inclusion Criteria:

• Documented keloids of pfannenstiel incision or midline subumbilical incision of one to five years duration.

• Previous treatment of keloid and recurrence.

• Patient complaint of cosmetic disfiguring, pain or pruritis at site of scar.

Exclusion criteria:

• Scar <1 years' duration

• Scar extending beyond the limits of the original lesion

• postburn keloids

• Diabetes Mellitus, anaemia (haemoglobin level <10mg/dL), malignancy, malnutrition.

• local inflammation at site of scar

• Allergy to dexamethasone.

• Immunocompromized patients or patients on chronic steroid treatment.