Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation

• Status: Completed
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators intend to perform a prospective randomized study and compare the incidence of surgical wound infection between mastectomy wounds irrigated with triple antibiotic solution (one side) and 0.05% CHG (opposite side) in patients undergoing bilateral breast reconstruction. Each patient will receive triple antibiotic solution on one breast and the CHG on the other breast.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vanderbilt University; Vanderbilt University Medical Center
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacitracin; Bacitracin zinc, neomycin sulfate, polymyxin B, drug combination; Cefazolin; Chlorhexidine; Chlorhexidine gluconate; Gentamicins; Neomycin; Pharmaceutical Solutions; Polymyxin B

Criteria

Inclusion Criteria:

• females between 18 - 81 years of age

• and are undergoing bilateral mastectomy

• and are candidates for immediate breast reconstruction with tissue expanders.

Exclusion Criteria:

• females younger than 18 and older than 81 years of age;

• undergoing unilateral mastectomy and reconstruction;

• bilateral reconstruction using other techniques,

• patients allergic to one or more components of the antibiotic solution;

• allergy to CHG