Switching From Ticagrelor to Prasugrel in Patients With Acute Coronary Syndrome

• Status: Not yet recruiting
• Trial end date: 2025-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study proposes to conduct the switch from ticagrelor to prasugrel in an organized stepwise manner, to allow for the evaluation of the relative efficacy of prasugrel versus ticagrelor using a stepped-wedge cluster randomized trial design.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vastra Gotaland Region
• Collaborators: Region Gävleborg; Region Halland; Region Örebro County; Region Skane; University Hospital, Linkoeping; University Hospital, Umeå
• Treatments: Prasugrel Hydrochloride; Ticagrelor

Criteria

Inclusion Criteria:

• Patients hospitalized for Acute coronary syndrome, as defined by the European Society of Cardiology, at any hospital participating in the study, and included in the SWEDEHEART registry during index hospitalization

• Age ≥ 18 years.

Exclusion Criteria:

• Patients on oral anticoagulation therapy

• Previous stroke