Overview

Sympathetic Mechanisms in the Cardiovascular and Metabolic Alterations of Obesity

Status:
Recruiting
Trial end date:
2025-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to study the role of sympathetic mechanisms involved in chronic regulation of cardiovascular and metabolic abnormalities seen in obesity. The investigators will study the effects chronic sympathetic inhibition on insulin sensitivity, inflammation and endothelial function in obese hypertensive human subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Italo Biaggioni
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Amlodipine
Moxonidine