This study has the following primary aim:
- the main objective of this study is to investigate the effects of smoking cessation during
quit attempts on sympathovagal balance. These effects will be observed in smokers quitting
smoking with pharmacological support or without.
Secondary aims of this study are also:
- the definition of MSNA in smokers and non-smokers
- the investigation of other parameters concerning the autonomic nervous system, like
baroreflex-sensitivity, heart rate-variability before and during the quit attempt.
- the definition of withdrawal symptoms and craving before, during and after the quit
attempt.
- the investigation of effects of smoking cues on craving and sympathovagal balance
- the investigation of relapse rates after smoking cessation in correlation with the
parameters mentioned above.
Phase:
Phase 4
Details
Lead Sponsor:
Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH