Symptomatic Efficacy of Diacerein in Knee Osteoarthritis

• Status: Completed
• Trial end date: 2006-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Pain is the main symptom of osteoarthritis that motivates medical visits. Diacerhein has already demonstrated its efficacy in knee and/or hip osteoarthritis. This study aims at confirming the efficacy of diacerhein in symptomatic knee osteoarthritis using known and validated criteria and according to the recommendations and guidelines for this kind of study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Laboratoires NEGMA
• Treatments: Diacetylrhein

Criteria

Inclusion Criteria:

• Painful primary osteoarthritis (VAS ≥ 40 mm)

• Radiologically proven (Kellgren & Lawrence grade I to III)

• Requiring the prescription of a symptomatic treatment of pain

Exclusion Criteria:

• Severe associated diseases

• Wash-out: AINS, Coxibs, Paracetamol, anti-osteoarthritic treatments, hyaluronic acid, knee tidal lavage

• Other osteoarticular disease