Overview

Systematic Withdrawal of Neurohumoral Blocker Therapy in Optimally Responding CRT Patients

Status:
Completed
Trial end date:
2019-02-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to demonstrate that in patients with recuperated/normalized left ventricular function, defined as an ejection fraction (EF) ≥ 50%, after implantation of cardiac resynchronization therapy, device treatment is sufficient and neurohumoral blocker therapy can safely be withdrawn
Phase:
Phase 4
Details
Lead Sponsor:
Hasselt University
Collaborator:
Ziekenhuis Oost-Limburg
Treatments:
Adrenergic beta-Antagonists
Angiotensin-Converting Enzyme Inhibitors
Spironolactone