Systolic Hypertension in the Elderly Program (SHEP)
Status:
Completed
Trial end date:
1996-10-01
Target enrollment:
Participant gender:
Summary
The primary objective was to assess whether long-term administration of antihypertensive
therapy to elderly subjects with isolated systolic hypertension reduced the combined
incidence of fatal and non-fatal stroke. The secondary objectives were to evaluate: the
effect of long-term antihypertensive therapy on mortality from any cause in elderly people
with isolated systolic hypertension; possible adverse effects of chronic use of
antihypertensive drug treatment in this population; the effect of therapy on indices of
quality-of-life; the natural history of isolated systolic hypertension in the placebo
population.