Systolic Hypertension in the Elderly Program (SHEP)
Status:
Completed
Trial end date:
1996-10-01
Target enrollment:
0
Participant gender:
All
Summary
The primary objective was to assess whether long-term administration of antihypertensive
therapy to elderly subjects with isolated systolic hypertension reduced the combined
incidence of fatal and non-fatal stroke. The secondary objectives were to evaluate: the
effect of long-term antihypertensive therapy on mortality from any cause in elderly people
with isolated systolic hypertension; possible adverse effects of chronic use of
antihypertensive drug treatment in this population; the effect of therapy on indices of
quality-of-life; the natural history of isolated systolic hypertension in the placebo
population.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator:
National Institute on Aging (NIA)
Treatments:
Atenolol Chlorthalidone Reserpine
Criteria
Men and women, aged 60 or over, with isolated systolic hypertension.