Overview

T-DM1 and Non-pegylated Liposomal Doxorubicin in HER2-positive Metastatic Breast Cancer

Status:
Completed
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The primary goal is to determine the maximum tolerated dose (MTD) of the combination of T-DM1 and non-pegylated liposomal doxorubicin in metastatic breast cancer (mBC) patients previously treated with taxanes and trastuzumab-based therapy. In addition, pharmacokinetic data on the combination of T-DM1 and lyposomal doxorubicin will be obtained.
Phase:
Phase 1
Details
Lead Sponsor:
MedSIR
Collaborators:
Experior
Roche Pharma AG
Treatments:
Ado-trastuzumab emtansine
Doxorubicin
Liposomal doxorubicin
Trastuzumab