TEAM: Testosterone Supplementation and Exercise in Elderly Men

• Status: Completed
• Trial end date: 2010-11-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to evaluate the effects of testosterone supplementation (AndroGel) on body composition, strength, endurance, cognition, and function in older men.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Colorado, Denver
• Collaborator: National Institute on Aging (NIA)
• Treatments: Methyltestosterone; Testosterone; Testosterone 17 beta-cypionate; Testosterone enanthate; Testosterone undecanoate

Criteria

Inclusion Criteria:

• Generally healthy, untrained men 60 years or older with low-normal testosterone levels (200-350ng/dL)

• Must reside in the Denver metro area

Exclusion Criteria:

• Prostate/breast cancer

• Unable to exercise safely

• severe obesity (>34 body mass index [BMI])

• Polycythemia

• Diabetes

• Use of drugs that could affect T levels

• Cognitive dysfunction (MMSE less than 24)

• PSA above the age-adjusted normal level or AUA greater than 19

• Unable to pass stress test due to active CAD