TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY
Status:
Recruiting
Trial end date:
2023-06-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to assess the feasibility of treatment with bintrafusp
alfa combined with definitive chemoradiation (carboplatin, paclitaxel and radiation) in
patients with squamous cell carcinoma of the esophagus or gastroesophageal junction.
Phase:
N/A
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Collaborators:
Catharina Ziekenhuis Eindhoven Deventer Ziekenhuis Elisabeth-TweeSteden Ziekenhuis Erasmus Medical Center Isala Leiden University Medical Center Maastro Clinic, The Netherlands Medisch Centrum Leeuwarden Radiotherapeutic Institute Friesland Radiotherapy Group Deventer Rijnstate Hospital The Netherlands Cancer Institute UMC Utrecht University Medical Center Groningen Verbeeten Insituut Tilburg ZGT Zuyderland Medisch Centrum