THRomboprophylaxis in Individuals Undergoing Superficial endoVEnous Treatment (THRIVE)
Status:
Not yet recruiting
Trial end date:
2026-08-31
Target enrollment:
Participant gender:
Summary
Endovenous interventions are keyhole operations for varicose veins that are carried out from
within the vein itself. Varicose veins are enlarged veins close to the surface of the skin.
They are connected to the bigger deeper veins in the leg (known as deep veins). Because of
this, operations to close the varicose veins can increase the chance of a blood clot forming
in the deep veins. Blood clots in the deep veins happen in around 1 in 50 people after
endovenous operations. A clot in the leg can cause swelling, pain, and other long-term
problems. If a clot in the leg breaks off and travels to the lungs, it can cause problems
with the lung' ability to move oxygen from the air into the blood and may, in rare cases, be
life threatening.
Varicose vein procedures may carry a slightly higher risk of blood clot formation, and we are
currently unsure if current clot reducing medicines are beneficial in preventing blood clots
in people having varicose vein procedures.
This study will investigate if it is worthwhile prescribing medicines to reduce blood clots
after varicose vein procedures.