Tacrolimus to Sirolimus Conversion for Delayed Graft Function
Status:
Terminated
Trial end date:
2014-07-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to evaluate the safety and efficacy of conversion from
tacrolimus to sirolimus early after kidney transplantation in patients with delayed graft
function (DGF)and slow graft function (SGF) in improving graft function and delaying chronic
allograft nephropathy. The investigators hypothesize that conversion from tacrolimus to
sirolimus in renal transplant recipients with DGF/SGF in early months after surgery will
improve graft function and decrease the progression of graft fibrosis.
Phase:
Phase 4
Details
Lead Sponsor:
University of Maryland University of Maryland, Baltimore