Overview Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer Status: Recruiting Trial end date: 2022-12-01 Target enrollment: Participant gender: Summary This study will examine the combination of pembrolizumab and tadalafil for safety and efficacy in advanced head and neck cancer. Phase: Phase 2 Details Lead Sponsor: University of California, San DiegoTreatments: PembrolizumabTadalafil