Overview Talazoparib for Cohesin-Mutated AML and MDS With Excess Blasts Status: Recruiting Trial end date: 2023-06-01 Target enrollment: Participant gender: Summary This research study is testing if Talazoparib is an effective treatment for patients with AML and MDS that have a mutation in the cohesin complex. Phase: Phase 1 Details Lead Sponsor: Dana-Farber Cancer InstituteCollaborator: PfizerTreatments: Talazoparib