Tamoxifen and Clomiphene Citrate in Mild Stimulation IVF

• Status: Unknown status
• Trial end date: 2019-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this prospective cohort study is to compare IVF outcome between tamoxifen and clomiphene citrate in mild stimulation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
• Collaborator: Sun Yat-sen University
• Treatments: Chorionic Gonadotropin; Citric Acid; Clomiphene; Enclomiphene; Tamoxifen; Zuclomiphene

Criteria

Inclusion Criteria:

1. age between 37 and 42;

2. BMI≤23kg/m2;

3. ≤3 oocytes with a conventional stimulation protocol;

4. AFC<5 follicles or AMH<1.1 ng/ml on the day 1 to 5 of the menses;

5. Cause of Infertiity: tubal factor, male factor, diminished ovarian reserve.

Exclusion Criteria:

1. endormetrial polyp, endormetrial cancer,intrauterine adhesions,uterine fibroids that affects uterine cavity

2. Endometriosis, adenomyosis

3. The diameter of Hydrosalpinx >2cm