Overview Tapentadol vs Tramadol in Total Knee Arthroplasty Status: RECRUITING Trial end date: 2025-06-01 Target enrollment: Participant gender: Summary Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).Phase: PHASE4 Details Lead Sponsor: University of ThessalyTreatments: TapentadolTramadol