Targeted Therapy Using Intradermal Injection of Etanercept for Remission Induction in Discoid Lupus Erythematosus
Status:
Completed
Trial end date:
2017-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether Etanercept which is given through
intradermal injection is effective in the treatment of discoid lupus erythematosus (DLE).
The investigators also would like to develop new tests to measure skin inflammation by
scanning the affected skin using optical coherence tomography (OCT), thermography and laser
doppler imaging (LDI) and taking photographs of the rash (to be done before and after
treatment). If the findings from these new tests are similar to the ones from taking a sample
of skin (biopsy), then the latter (which is an invasive test) can be avoided.
Phase:
Phase 2
Details
Lead Sponsor:
University of Leeds
Collaborators:
Clinical Trials Research Unit, Leeds National Institute for Health Research, United Kingdom Pfizer