Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
Status:
Completed
Trial end date:
2016-11-20
Target enrollment:
Participant gender:
Summary
The investigator's global hypothesis is that women with Polycystic Ovary Syndrome (PCOS) can
be separated into subtypes based on their response to metformin. The investigators propose
here to use both targeted and non-targeted metabolomic approach to identify pathways
associated with metformin's effect on insulin sensitivity and endothelial function. This
pilot project will be the foundation for developing tailored therapeutic approaches to
Polycystic Ovary Syndrome and identifying novel drug targets.