Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind.
Status:
Enrolling by invitation
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
This is a single center brain Positron Emission Tomography (PET) study of 18F-MK-6240.
Eligible participants are persons from Northern Manhattan who self-identify as Hispanic,
non-Hispanic Black, or Non-Hispanic White, who are 55 to 69 years of age, of both sexes,
without dementia, who have already agreed to undergo, of have undergone, brain amyloid PET
and magnetic resonance imaging (MRI). Those eligible will have one brain PET scan with
18F-MK-6240, repeated after 18 months to 30 months. Vital signs will be checked prior to
injection of 18F-MK-6240 and again at the completion of the PET scan. The primary objective
is to relate diabetes status and glycemia to in-vivo brain tau accumulation, across and
within ethnic and racial groups.
Phase:
Phase 2
Details
Lead Sponsor:
Columbia University
Collaborators:
Hebrew Home at Riverdale National Institute on Aging (NIA)