Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as temozolomide, vincristine, and irinotecan,
work in different ways to stop the growth of tumor cells, either by killing the cells or by
stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill
more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of irinotecan when
given together with temozolomide and vincristine in treating young patients with refractory
solid tumors.