Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop
the growth of tumor cells, either by killing the cells or by stopping them from dividing.
Everolimus may stop the growth of tumor cells by blocking blood flow to the tumor and by
blocking some of the enzymes needed for cell growth. Giving everolimus together with
temozolomide may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving everolimus together with
temozolomide works in treating patients with stage IV melanoma that cannot be removed by
surgery