Temozolomide and Thalidomide in Treating Patients With Stage III or Stage IV Melanoma
Status:
Completed
Trial end date:
2004-08-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Thalidomide may stop the growth of melanoma by stopping blood flow
to the tumor. Combining chemotherapy with thalidomide may kill more tumor cells.
PURPOSE: Phase I/II trial to study the effectiveness temozolomide plus thalidomide in
treating patients who have stage III or stage IV melanoma that cannot be removed during
surgery.