Temozolomide for Relapsed Sensitive or Refractory Small Cell Lung Cancer
Status:
Completed
Trial end date:
2013-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether treatment with temozolomide will shrink
small cell lung cancer tumors. Temozolomide is an oral chemotherapy drug that is currently
used to treat brain cancer and melanoma.
As part of this study, we will be doing additional tests that may help us understand how
temozolomide works. First, if there is a tumor sample from a biopsy done in the past, it will
be analyzed for an abnormal gene that may be present in lung cancer. Before starting
temozolomide, a research blood test will be done to look for the same abnormal gene we are
looking for in your tumor sample. Also, before starting temozolomide and every time you have
a repeat CT scan, a research blood test will be done to analyze the number of tumor cells in
your bloodstream.