Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs

• Status: Completed
• Trial end date: 2017-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study aims to look at the effect of terlipressin infusion on blood loss and blood transfusion needs during Whipple procedure

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Lypressin; Terlipressin

Criteria

Inclusion Criteria:

• All patients older than 18 years of age,

• ASA classification class I and II,

• Patients assigned for Whipple procedure.

Exclusion Criteria:

• Preoperative renal failure,

• Severe liver dysfunction (Child-Turcotte-Pugh grade C),

• Hyponatremia (Na+ <132mmol/l),

• Severe valvular heart disease,

• Heart failure,

• Symptomatic coronary heart disease,

• Bradycardic arrhythmia (heart rate < 60/min),

• Peripheral artery occlusive disease (clinical stadium II-IV),

• Uncontrolled arterial hypertension (Blood pressure >160/100mmHg despite intensive treatment),

• Pregnancy.