Terlipressin in Cirrhotic Patients With Recidivation Ascites Treated With Paracentesis and Albumin
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
Ascites is a common complication of cirrhosis. Sodium restriction and diuretics are the first
step treatment. Refractory ascites (not responding to first step treatment) is treated with
repeated large volume paracentesis followed by intra venous albumin expansion. In pilot
studies vasoconstrictor agents such as terlipressin have shown beneficial effect on ascites
production. Therefore the investigators will study the effect of combined therapy with
albumin and terlipressin on recidivation ascites.