Test Predicting Adrenal Insufficiency in Volunteers Under Prednisone Treatment

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

Suppression of the adrenal function is a common, potentially dangerous and unpredictable consequence of short term high dose glucocorticoid treatment. Identification of patients at risk would be of high clinical importance. The investigators hypothesized that the dexamethasone-suppression-test predicts the subsequent development of corticosteroid induced adrenal insufficiency.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospital, Basel, Switzerland
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Epinephrine; Epinephryl borate; Prednisone; Racepinephrine

Criteria

Inclusion Criteria:

• Healthy male volunteers over 18 years

Exclusion Criteria:

• No informed consent

• Intake of any kind of medication

• BMI over 30kg/m2

• Acute or chronic illnesses