Testosterone Gel in Poor Responders Undergoing IVF

• Status: Withdrawn
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

The main purpose of this study is to compare the number of oocytes retrieved after using transdermal testosterone gel 10 mg per day or Dehydroepiandrosterone (DHEA) 75mg per day for 6-8 weeks as pre-treatment for poor ovarian responders undergoing in-vitro fertilization (IVF).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Vietnam National University
• Collaborator: Mỹ Đức Hospital
• Treatments: Dehydroepiandrosterone; Methyltestosterone; Testosterone; Testosterone 17 beta-cypionate; Testosterone enanthate; Testosterone undecanoate

Criteria

Inclusion Criteria:

To be eligible for enrolment into this trial, each female subject must fulfill all of the following criteria at the start of enrolment, unless specified otherwise:

• Had one or two previous failure IVF cycle, using GnRH antagonist protocol (≥ 300 IU FSH/hMG per day) and the number of retrieved oocytes are ≤ 3;

• Antral follicle counts (AFC) < 6 or Anti-Mullerian Hormone (AMH) < 1.26 ng/ml

Exclusion Criteria:

To be eligible for enrolment in this study each subject must not meet any of the following criteria:

• Oocyte donation cycle

• Patients have thyroid disease

• Patients have liver or kidney dysfunction

• Patients have abnormal puberty or genital development.

• Patients have previous surgery on ovaries