Men infected with the HIV virus (the virus that causes AIDS) often lose weight even though
they may try to eat more food to gain weight. The reasons for this weight loss are not clear.
Many men with HIV have low levels of testosterone in their blood. Testosterone is a hormone
that is naturally produced in the bodies of both men and women and has important effects on
building muscle and bone mass. The purpose of this study is to find out if providing
additional testosterone to HIV infected men who have low testosterone can help them gain
weight, increase their muscle mass, and feel better. The study will also help see if
testosterone improves the efficiency with which your body produces and uses energy including
fat. The dose of testosterone being used in this study will raise testosterone levels in the
blood to higher than normal levels (2-3 times normal level).
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)