Testosterone for Men With Insulin Treated Type 2 Diabetes

• Status: Completed
• Trial end date: 2008-10-01
• Target enrollment: 0
• Participant gender: Male

Summary

The purpose of this study is to test the effect of testosterone treatment on glycaemic control, arterial stiffness and IMT in hypogonadal men with type 2 diabetes treated with insulin.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Barnsley Hospital
• Treatments: Methyltestosterone; Testosterone; Testosterone 17 beta-cypionate; Testosterone enanthate; Testosterone undecanoate

Criteria

Inclusion Criteria:

• males over 40 years old

• type 2 diabetes treated with insulin

• serum testosterone less than 12nmol/L on 2 consecutive morning samples

• symptoms attributable to hypogonadism

Exclusion Criteria:

• current or previous breast cancer

• current or previous prostate cancer

• raised prostate specific antigen or abdominal digital rectal examination suspicious of prostate cancer unless diagnosis excluded after specialist urology opinion and/or prostate biopsy

• severe symptoms of benign prostatic hypertrophy

• treatment with testosterone in the three months prior to the trial

• investigational drug treatment in the three months prior to the trial