Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE

• Status: Terminated
• Trial end date: 2011-12-12
• Target enrollment: 0
• Participant gender: Female

Summary

The investigators hypothesis is that spinal tetracaine with fentanyl and epinephrine used for CSE labor analgesia volume will last a significantly longer period of time that that of spinal bupivacaine with fentanyl. After informed consent is obtained for the study, subjects meeting criteria when analgesia is requested will be randomized to receive a combined spinal-epidural containing either tetracaine 2 mg with fentanyl and epinephrine or bupivacaine 2 mg with fentanyl and epinephrine.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wake Forest School of Medicine; Wake Forest University
• Treatments: Bupivacaine; Epinephrine; Epinephryl borate; Fentanyl; Racepinephrine; Tetracaine

Criteria

Inclusion Criteria:

• early labor (>=2cm but =<6cm cervical dilation)

• at least 12 years of age

• have an assigned ASA physical status 1 or 2

• singleton pregnancy

Exclusion Criteria:

• contraindications to neuraxial anesthesia

• with allergies to drugs used in the study

• have an assigned ASA status 3 or 4

• advanced labor (> 6cm cervical dilation)

• less than 12 years of age

• Patients with the potential for distorted epidural anatomy, such as Harrington rods or prior back surgery, will also be excluded.