Texture Analysis for Postmenopausal Osteoporosis

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine if a new test for osteoporosis can be useful in monitoring treatment. We are studying a new method for examining the quality of bone by an experimental method of computerized analysis of radiographic images (x-ray pictures) of the heel.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Chicago
• Collaborators: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS); National Institutes of Health (NIH)
• Treatments: Alendronate; Calcium; Calcium, Dietary; Citric Acid; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• The study will enroll 40 postmenopausal women with a T score < -2 either at the lumbar spine or the femoral neck: 20 who decide to begin anti-resorptive therapy (treated group), and 20 women who decline such therapy (control group). We will attempt to match the patients and the controls for T score (within 0.3) and age (within 5 years).

• All study participants will be:

• at least 3 years past the last menstrual period,

• not on HRT, Raloxifene or calcitonin for at least 6 months.

Exclusion Criteria:

• All study participants will not be on bisphosphonates during the previous 12 months.

• Women with secondary causes of osteoporosis will be excluded.