Thalidomide and Cyclophosphamide in Treating Children With Recurrent or Refractory Childhood Cancers
Status:
Completed
Trial end date:
2001-07-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Thalidomide may kill tumor cells by stopping the growth of new blood vessels to
the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining thalidomide with chemotherapy may kill more tumor cells.
PURPOSE: Phase II trial to study the effectiveness of combining thalidomide and
cyclophosphamide in treating children who have recurrent or refractory childhood cancers.