The Analgesic Efficacy of Oxycodone Hydrochloride Versus Fentanyl After Total Hip Arthroplasty:
Status:
Not yet recruiting
Trial end date:
2023-01-30
Target enrollment:
Participant gender:
Summary
Oxycodone showed similar or superior analgesic effects than fentanyl and was proposed as an
alternative for fentanyl for pain control in the postoperative period. However, it was mainly
directed to control visceral pain, due to the mediation of analgesic effects by the kappa
receptors. However, few studies compared the oxycodone to fentanyl for postoperative pain
relief in patients undergoing total hip arthroplasty (replacement). Therefore, we established
this randomized study to compare the efficacy of oxycodone and fentanyl for relief of
postoperative pain after total hip arthroplasty (replacement).