The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections

• Status: Completed
• Trial end date: 2013-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The inferior alveolar nerve block (shot) is the most frequently used injection technique for achieving local anesthesia (numbness) for the teeth in the lower jaw. However, this injection does not always result in successful pulpal (tooth) anesthesia (patient felt pain). No study has combined mepivacaine and lidocaine anesthetics (numbing solutions) for this type of injection (shot). The investigators propose to compare an injection of mepivacaine followed by lidocaine to an injection of lidocaine followed by lidocaine to determine if there is a difference in effectiveness.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ohio State University
• Treatments: Anesthetics; Epinephrine; Epinephryl borate; Lidocaine; Mepivacaine; Racepinephrine

Criteria

Inclusion Criteria:

• between the ages of 18 and 65 years

• good health (ASA classification I or II)

• able to provide informed consent

Exclusion Criteria:

• allergy to lidocaine or mepivacaine

• history of significant medical problem (ASA classification III or greater)

• depression

• have taken CNS depressants (including alcohol or any analgesic medications) within the last 48 hours

• lactating or pregnant

• inability to give informed consent