The Antibacterial Effect of Nanosilver Fluoride on Primary Teeth

• Status: Not yet recruiting
• Trial end date: 2022-06-01
• Target enrollment: 0
• Participant gender: All

Summary

To assess the antibacterial effect of Nanosilver Fluoride (NSF) in relation to caries activity in dentin caries lesions of primary teeth in comparison to Silver Diamine Fluoride (SDF).

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Nour Ammar
• Treatments: Fluorides

Criteria

Inclusion Criteria:

• The presence of at least one active carious lesion on a primary tooth.

• Completion of an informed consent to participate in the study.

Exclusion criteria:

• Children reporting spontaneous or elicited pain from caries or showing any signs of pulpal infection, swelling, abscess, obvious discoloration of the tooth, or premature mobility.

• Reported usage of local or systemic antibiotics, chlorhexidine or fluoride mouthwashes within the last 2 weeks.

• Children presenting with special health care needs or undergoing medical treatment for chronic or acute diseases affecting salivary flow.

• Allergy or sensitivity to silver or any of the materials included in the study.

• Child weight less than 10 Kg (to avoid concerns for toxicity).