The Assessment of Tranexamic Acid in Women With Menorrhagia Who Have Bleeding Disorders
Status:
Completed
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
Many women have heavy periods and this can be associated with low blood, tiredness and
inability to carry out normal activities. Approximately 10-30% of these women will have an
underlying bleeding disorder. There is a drug called tranexamic acid which is commonly used
and is effective in reducing menstrual flow. However, up to 1/3 of women have side effects
and they are more common at higher doses. In the medical literature, there are different
dosing schedules and there is one commonly recommended in Canada. Women with underlying
bleeding disorders may require higher doses of this medication compared to those who do not.
In this study, the investigators want to find the lowest effective dose of tranexamic acid
for girls and women with heavy periods who have bleeding disorders and the investigators
think this will be lower then the usual recommended dose. If the investigators' results
support this, it may contribute to changing how the investigators presently prescribe this
medication and may provide a better option for women with heavy periods in particular those
with bleeding disorders. The investigators have just started a Women with Bleeding Disorders
Clinic and hope that this project will lead to better care for the patients and more research
in the future.