Overview

The Bupivacaine Dose Sparing Effect of Intrathecal Epinephrine

Status:
Completed
Trial end date:
2011-07-01
Target enrollment:
0
Participant gender:
All
Summary
Intrathecal epinephrine has been known to increase the duration of spinal anesthesia, or increase the quality of anesthesia. However, there is still a controversy, and the mechanism of epinephrine is recently suggested as a modulator of pain information in the spinal cord. Therefore, the investigators try to investigate the dose sparing effect of intrathecal epinephrine for spinal anesthesia with bupivacaine.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Seoul Medical Center
Treatments:
Anesthetics
Bupivacaine
Epinephrine
Epinephryl borate
Racepinephrine
Criteria
Inclusion Criteria:

- patient undergoing total knee replacement arthroplasty

Exclusion Criteria:

- patient with cardiac or pulmonary disease (ASA class III or more)

- patient undergone previous spine surgery

- patient undergoing revised knee replacement