Overview

The CHAPS Trial: Combined HIV Adolescent PrEP and Prevention

Status:
Recruiting
Trial end date:
2021-08-30
Target enrollment:
Participant gender:
Summary
To compare the effect of different PrEP drugs (FTC-TDF and FTC-TAF), doses and timing of doses on p24 antigen level in resected foreskin tissue following HIV exposure ex vivo challenge.
Phase:
Phase 2
Details
Lead Sponsor:
Fatima Mayat
Wits Health Consortium (Pty) Ltd
Collaborators:
Imperial College London
Karolinska Institutet
King's College London
London School of Hygiene and Tropical Medicine
MRC/UVRI Uganda Research Unit
University of Cape Town
University of Liverpool
Treatments:
Emtricitabine
Tenofovir