The Community Effectiveness of IPTi in Southern Tanzania
Status:
Unknown status
Trial end date:
2008-12-01
Target enrollment:
Participant gender:
Summary
The safety and efficacy of Intermittent Preventive Treatment for malaria and anaemia control
in Infants (IPTi) have already been documented in Southern Tanzania, affording an opportunity
to gain operational experience in developing a strategy for the longer-term implementation of
IPTi. Working in conjunction with national and district-based health authorities, a strategy
will be developed to make IPTi available through routine health services and an effectiveness
evaluation conducted. This will be based on the comparison of process and outcome indicators
in areas with and without IPTi. Information on safety will be consolidated and the effect of
IPTi on the rate of development of drug resistance explored. The acceptability and costs of
implementing IPTi will be monitored and combined with assessments of effectiveness (in terms
of morbidity and mortality) to assess the cost-effectiveness of IPTi.
Phase:
Phase 3
Details
Lead Sponsor:
Swiss Tropical & Public Health Institute
Collaborators:
Hospital Clinic of Barcelona Ifakara Health Research and Development Centre London School of Hygiene and Tropical Medicine Ministry of Health, Tanzania
Treatments:
Fanasil, pyrimethamine drug combination Pyrimethamine Sulfadoxine